Terapias avanzadas, diferenciación, regeneración, cáncer.
Grupo: CTS 963
Formación Académica
Licenciatura en Biología
Facultad de Ciencias, Universidad de Granada. España. 2003-2009
Master en Biomedicina Regenerativa
Departamento de Anatomía y Embriología Humana, Facultad de Medicina, Universidad de Granada. España. 2010
Proyectos
Título: Proyecto de Excelencia- BIOMER CONDROSTEM 3-D: biomedicina regenerativa de patología condral mediante el uso células madre autólogas CTS-6568
Entidad financiadora :Consejería de Innovación, Ciencia y Empresa
Duración: 2011-2014
IP: Juan Antonio Marchal Corrales
2010 - present
2010 - present
Publicaciones
• García MA, Carrasco E, Ramírez A, Jiménez G, López-Ruiz E, Perán M, Picón M, Campos J. Marchal JA. Apoptosis as a Therapeutic Target in Cancer and Cancer Stem Cells: Novel Strategies and Futures Perspectives.Libro Apoptosis 2.Tobias M. Ntuli (Ed), Intech, (2012) pp 1-44
• Perán M, García MA, López-Ruiz E, Bustamante M, Jiménez G, Madeddu R, Marchal JA. Functionalized nanostructures with application in regenerative medicine.Int J Mol Sci.(2012)13, 3847- 3886
• López-Ruiz E, Perán M, Cobo-Molinos J, Jiménez G, Picón M, Bustamante M, Arrebola F, Hernández-Lamas MC, Delgado-Martínez AD, Montañez E, Marchal JA. Chondrocytes extract from patients with osteoarthritis induces chondrogenesis in infrapatellar fat pad-derived stem cells. OsteoarthritisCartilage. (2013) 21(1):246-58.
• Perán M, García MA, López Ruiz E, Jiménez G, Marchal JA. How Can Nanotechnology Help to Repair the Body? Advances in Cardiac, Skin, Bone, Cartilage and Nerve Tissue Regeneration.Materials (2013), 6(4), 1333-1359.
• Marchal JA, Carrasco E, Ramirez A, Jiménez G, Olmedo C, Peran M, Agil A, Conejo-García A, Cruz-López O, Campos JM, García MÁ. Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence. Drug Des Devel Ther. (2013) ;7:1301-13.
• Ramírez A, Boulaiz H, Morata C, Perán M, Jiménez G, Picon-Ruiz M, Agil A, Cruz-López O, Conejo-García A, Campos JM, Sánchez A, García MA , Marchal JA. HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound. Oncotarget (2014); 15;5(11):3590-606.
Contribuciones a congresos
• XVII Congress in Cancer Society Andaluza. Malaga, Spain, 2010
Poster: Changes in the expression of beta-catenin after RTQT in preoperative rectal cancer. Prognostic implications.
• 9th Joint Meeting of the International Cytokine Society (ICS) and the International Society for Interferon and Cytokine Research (ISICR). Florence, Italy, 2011
Poster: Interferon alpha enhances the antitumor activity of a novel purine derivative drug.
• I International Symposium on Cell and Gene-Based Therapies. Granada, Spain, 2012
Poster: Role of sox9 in chondrogenesis of mesenchymal stem cells isolated from the infrapatellar fat.
• I Joint Congress of the Spanish Knee Society (SEROD) and the Spanish Arthroscopy Association (AEA). San Sebastian, Spain. 2013
Oral communication: Chondrogenic potential of stem cells from fat Hoffa induced chondrocyte extracts.
• I Joint Congress of the Spanish Knee Society (SEROD) and the Spanish Arthroscopy Association (AEA). San Sebastian, Spain. 2013
Poster: Role of SOX-9 in chondrocyte differentiation of the stem cells isolated from infrapatellar fat pad of patients with osteoarthritis.
• 5th European Symposium on Ultrasonic Characterization of Bone. Granada, Spain, 2013
Oral communication: Real-time probabilistic model-based monitoring biorreactor for engineered cartilage.
• XII Spanish Congress on Environmental Health. Granada, Spain, 2013
Poster: Breast cancer stem cell response to radiation.
• XVII Congress of the Spanish Society of Radiation Oncology. Vigo, Spain, 2013
Poster: Stem- like cells from breast cancer: crucial players in cellular response to radiotherapy.
• First Meeting of phd Researchers of the University of Jaén. Jaén, Spain, 2013
Oral communication: Decellularization and reendothelialization of blood vessel for use in regenerative medicine.